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100% Original Guanidine Hydrochloride China - Aminoguanidine Hydrochloride – Hailun New Material

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We are experienced manufacturer. Wining the majority of the crucial certifications of its market for Aminoguanidine Diabetic Nephropathy, Aminoguanidine Hydrochloride Osha Hazards, Aminoguanidine Inhibitor, We have ISO 9001 Certification and qualified this product .over 16 years experiences in manufacturing and designing, so our products featured with best quality and competitive price. Welcome cooperation with us!
100% Original Guanidine Hydrochloride China - Aminoguanidine Hydrochloride – Hailun New Material Detail:

Product name:carbazamidine hydrochloride; (diaminomethylidene)hydrazinium chloride
Molecular Formula:CH6N4HCL
CAS1937-19-5
Molecular Weight:110.55
Structural Formula:

yy1

 

Use:Pharmaceutical, veterinary drugs

Index name

Index Value

Appearance

White like crystalline powder

Content

98%

99%

Insoluble Substances

0.2%

0.1%

Loss on Drying

1.5%

1%

Ignition Residue

0.2%

0.1%

Iron Content(Fe)

10 ppm

6 ppm

Free Acid

0.8%

0.5%

preparation

Preparation of aminoguanidine hydrochloride: 9 g of aminoguanidine carbonate was put into a 250ml three port flask, 20ml of absolute ethanol was added, the solid was insoluble in anhydrous ethanol to form a suspension. Under stirring at room temperature, the mixture of 6ml 30% concentrated hydrochloric acid and 10ml of absolute ethanol was dropwise added until there was no bubble, and then stirring reaction was continued at room temperature for 1 hour. The obtained suspension was heated to dissolve the solid completely, and then it was naturally lowered to room temperature. After being moved to the refrigerator and placed overnight, the white rod-shaped crystal with melting point of 166-167 was obtained.

Application

Daidzein has a variety of pharmacological effects, prevention and treatment of a variety of diseases. Cn200910144204.1 reported that aminoguanidine hydrochloride can be used to prepare a chemically modified daidzein, namely, daidzein 7,4 ‘- oxy aminoguanidine acetate. The soybean aglycone 7,4 ‘- oxy aminoguanidine acetate is a prodrug compound, which releases the parent drug – daidzein under physiological conditions, and improves its water solubility by covalent binding.

The preparation of Daidzein 7,4 - o-aminoguanidine acetate: 0.5g aminoguanidine hydrochloride was dissolved in 100ml acetone, 0.02g phase transfer catalyst, 0.5g anhydrous potassium carbonate, 0.5g 7,4 - chloroacetyl daidzein and 0.02g I2 were added into the solution. The reaction was carried out at room temperature for 24 hours. Acetone was evaporated from the filtrate under reduced pressure, and then separated by silica gel column. The eluent was ethyl acetate petroleum ether When the ratio is 1 2, the white powder solid is obtained.

 

 


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Assume full responsibility to meet all demands of our clients; achieve continuous advancements by promoting the growth of our clients; become the final permanent cooperative partner of clients and maximize the interests of clients for 100% Original Guanidine Hydrochloride China - Aminoguanidine Hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Brunei, Palestine, Cancun, To achieve reciprocal advantages, our company is widely boosting our tactics of globalization in terms of communication with overseas customers, fast delivery, the best quality and long-term cooperation. Our company upholds the spirit of "innovation, harmony, team work and sharing, trails, pragmatic progress". Give us a chance and we'll prove our capability. With your kind help, we believe that we can create a bright future with you together.
  • This is a very professional wholesaler, we always come to their company for procurement, good quality and cheap.
    5 Stars By Amelia from Grenada - 2017.06.19 13:51
    Products and services are very good, our leader is very satisfied with this procurement, it is better than we expected,
    5 Stars By Honey from Johannesburg - 2017.02.28 14:19
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