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China Supplier Aminoguanidine And Kidney And Infection - Guanidine hydrochloride – Hailun New Material

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China Supplier Aminoguanidine And Kidney And Infection - Guanidine hydrochloride – Hailun New Material Detail:

Product name: Guanidine Hydrochloride

Aminoformamidine hydrochloride or Guanidinium chloride

Appearance: white or yellowish lump.

Physical property data

1. Character: white or yellowish lump

2. Melting point (℃): 181-183

3. Relative density (g / ml, 20 / 4 ℃): 1.354

4. Solubility: 228g in 100g water, 76g in 100g methanol and 24g in 100g ethanol at 20 ℃. Almost insoluble in acetone, benzene and ether.

5. PH value (4% aqueous solution, 25 ℃): 6.4

Properties and stability

This product is unstable and can be hydrolyzed into ammonia and urea in aqueous solution, so its toxicity is the same as that of urea. Guanidine and its derivatives are generally more toxic than urea.

Purpose:1. It can be used as intermediate of medicine, pesticide, dye and other organic synthesis. It can be used to synthesize 2-Aminopyrimidine, 2-amino-6-methylpyrimidine and 2-amino-4,6-dimethylpyrimidine. It is an intermediate for the manufacture of sulfadiazine, sulfamethylpyrimidine and sulfadimidine.

 

2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize anti anemia drug folic acid. It can also be used as antistatic agent for synthetic fibers.

 

3. It can also be used as protein denaturant.

 

  1. As a strong denaturant in the experiment of extracting total RNA. Guanidine hydrochloride solution can dissolve protein, cause cell structure damage, nuclear protein secondary structure damage, dissociate from nucleic acid, in addition, RNase can be inactivated by reducing agent such as guanidine hydrochloride.

synthetic method

Using dicyandiamide and ammonium salt (ammonium chloride) as raw materials, the crude guanidine hydrochloride was obtained by melting reaction at 170-230 ℃, and the finished product was obtained by refining.

Contact control

1. Do not inhale dust

2. Harmful if swallowed

3. Eye irritation

4. Skin irritation

Personal protection

1. Wear protective clothing to avoid direct contact or inhalation; 2. Do not drink, eat or smoke at work; 3. Use safety glasses


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Our well-equipped facilities and great excellent command throughout all stages of generation enables us to guarantee total customer fulfillment for China Supplier Aminoguanidine And Kidney And Infection - Guanidine hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Australia, San Francisco, kazan, Our focus on product quality, innovation, technology and customer service has made us one of undisputed leaders worldwide in the field. Bearing the concept of "Quality First, Customer Paramount, Sincerity and Innovation" in our mind, We have achieved great progress in the past years. Clients are welcomed to buy our standard products, or send us requests. You will be impressed by our quality and price. Please contact us now!
  • The quality of the products is very good, especially in the details, can be seen that the company work actively to satisfy customer's interest, a nice supplier.
    5 Stars By Bernice from Argentina - 2017.03.28 16:34
    A nice supplier in this industry, after a detail and careful discussion, we reached a consensus agreement. Hope that we cooperate smoothly.
    5 Stars By Beatrice from Uganda - 2017.03.08 14:45
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