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Chinese Professional Osha Hazards For Aminoguanidine Hydrochloride - Aminoguanidine Hydrochloride – Hailun New Material

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During the past few years, our business absorbed and digested state-of-the-art technologies the two at home and abroad. Meanwhile, our firm staffs a group of experts devoted to your development of Molecular Weight Aminoguanidine Hydrochloride, 3-Amino-1 2 4-Triazole Pubchem, 4-Amino-5-Phenyl-4h-1 2 4-Triazole-3-Thiol, We welcome customers all over the word to contact us for future business relationships. Our products are the best. Once Selected, Perfect Forever!
Chinese Professional Osha Hazards For Aminoguanidine Hydrochloride - Aminoguanidine Hydrochloride – Hailun New Material Detail:

Product name:carbazamidine hydrochloride; (diaminomethylidene)hydrazinium chloride
Molecular Formula:CH6N4HCL
CAS1937-19-5
Molecular Weight:110.55
Structural Formula:

yy1

 

Use:Pharmaceutical, veterinary drugs

Index name

Index Value

Appearance

White like crystalline powder

Content

98%

99%

Insoluble Substances

0.2%

0.1%

Loss on Drying

1.5%

1%

Ignition Residue

0.2%

0.1%

Iron Content(Fe)

10 ppm

6 ppm

Free Acid

0.8%

0.5%

preparation

Preparation of aminoguanidine hydrochloride: 9 g of aminoguanidine carbonate was put into a 250ml three port flask, 20ml of absolute ethanol was added, the solid was insoluble in anhydrous ethanol to form a suspension. Under stirring at room temperature, the mixture of 6ml 30% concentrated hydrochloric acid and 10ml of absolute ethanol was dropwise added until there was no bubble, and then stirring reaction was continued at room temperature for 1 hour. The obtained suspension was heated to dissolve the solid completely, and then it was naturally lowered to room temperature. After being moved to the refrigerator and placed overnight, the white rod-shaped crystal with melting point of 166-167 was obtained.

Application

Daidzein has a variety of pharmacological effects, prevention and treatment of a variety of diseases. Cn200910144204.1 reported that aminoguanidine hydrochloride can be used to prepare a chemically modified daidzein, namely, daidzein 7,4 ‘- oxy aminoguanidine acetate. The soybean aglycone 7,4 ‘- oxy aminoguanidine acetate is a prodrug compound, which releases the parent drug – daidzein under physiological conditions, and improves its water solubility by covalent binding.

The preparation of Daidzein 7,4 - o-aminoguanidine acetate: 0.5g aminoguanidine hydrochloride was dissolved in 100ml acetone, 0.02g phase transfer catalyst, 0.5g anhydrous potassium carbonate, 0.5g 7,4 - chloroacetyl daidzein and 0.02g I2 were added into the solution. The reaction was carried out at room temperature for 24 hours. Acetone was evaporated from the filtrate under reduced pressure, and then separated by silica gel column. The eluent was ethyl acetate petroleum ether When the ratio is 1 2, the white powder solid is obtained.

 

 


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Well-run products, skilled income group, and better after-sales products and services; We have been also a unified massive family, all people stick with the business price "unification, dedication, tolerance" for Chinese Professional Osha Hazards For Aminoguanidine Hydrochloride - Aminoguanidine Hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Dubai, Philippines, Cape Town, With strong technical strength and advanced production equipment, and SMS people purposefully , qualified, dedicated spirit of enterprise. Enterprises took the lead through the ISO 9001:2008 international quality management system certification, CE certification EU ; CCC.SGS.CQC other related product certification. We look forward to reactivating our company connection.
  • This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
    5 Stars By Marcia from Poland - 2018.06.19 10:42
    High Quality, High Efficiency, Creative and Integrity, worth having long-term cooperation! Looking forward to the future cooperation!
    5 Stars By Jane from UAE - 2017.09.28 18:29
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