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Factory directly Aminoguanidine Toxicity - Guanidine hydrochloride – Hailun New Material

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Factory directly Aminoguanidine Toxicity - Guanidine hydrochloride – Hailun New Material Detail:

Product name: Guanidine Hydrochloride

Aminoformamidine hydrochloride or Guanidinium chloride

Appearance: white or yellowish lump.

Physical property data

1. Character: white or yellowish lump

2. Melting point (℃): 181-183

3. Relative density (g / ml, 20 / 4 ℃): 1.354

4. Solubility: 228g in 100g water, 76g in 100g methanol and 24g in 100g ethanol at 20 ℃. Almost insoluble in acetone, benzene and ether.

5. PH value (4% aqueous solution, 25 ℃): 6.4

Properties and stability

This product is unstable and can be hydrolyzed into ammonia and urea in aqueous solution, so its toxicity is the same as that of urea. Guanidine and its derivatives are generally more toxic than urea.

Purpose:1. It can be used as intermediate of medicine, pesticide, dye and other organic synthesis. It can be used to synthesize 2-Aminopyrimidine, 2-amino-6-methylpyrimidine and 2-amino-4,6-dimethylpyrimidine. It is an intermediate for the manufacture of sulfadiazine, sulfamethylpyrimidine and sulfadimidine.

 

2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize anti anemia drug folic acid. It can also be used as antistatic agent for synthetic fibers.

 

3. It can also be used as protein denaturant.

 

  1. As a strong denaturant in the experiment of extracting total RNA. Guanidine hydrochloride solution can dissolve protein, cause cell structure damage, nuclear protein secondary structure damage, dissociate from nucleic acid, in addition, RNase can be inactivated by reducing agent such as guanidine hydrochloride.

synthetic method

Using dicyandiamide and ammonium salt (ammonium chloride) as raw materials, the crude guanidine hydrochloride was obtained by melting reaction at 170-230 ℃, and the finished product was obtained by refining.

Contact control

1. Do not inhale dust

2. Harmful if swallowed

3. Eye irritation

4. Skin irritation

Personal protection

1. Wear protective clothing to avoid direct contact or inhalation; 2. Do not drink, eat or smoke at work; 3. Use safety glasses


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"Sincerity, Innovation, Rigorousness, and Efficiency" is the persistent conception of our company for the long-term to develop together with customers for mutual reciprocity and mutual benefit for Factory directly Aminoguanidine Toxicity - Guanidine hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Somalia, Kenya, Dubai, As a way to make use of the resource on the expanding information and facts in international trade, we welcome prospects from everywhere on the web and offline. In spite in the top quality products and solutions we supply, effective and satisfying consultation service is supplied by our professional after-sale service group. Solution lists and thorough parameters and any other info weil be sent for you timely for the inquiries. So make sure you get in touch with us by sending us emails or contact us if you have any concerns about our firm. ou can also get our address info from our web site and come to our enterprise. or a field survey of our solutions. We're confident that we have been going to share mutual results and build solid co-operation relations with our companions in this market. We're looking forward to your inquiries.
  • Customer service staff and sales man are very patience and they all good at English, product's arrival is also very timely, a good supplier.
    5 Stars By Gladys from Turkey - 2018.08.12 12:27
    We have been engaged in this industry for many years, we appreciate the work attitude and production capacity of the company, this is a reputable and professional manufacturer.
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