China Factory wholesale Guanidine Hydrochloride Drug - Aminoguanidine Hydrochloride – Hailun New Material factory and suppliers

Factory wholesale Guanidine Hydrochloride Drug - Aminoguanidine Hydrochloride – Hailun New Material

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It adheres to the tenet "Honest, industrious, enterprising, innovative" to develop new products constantly. It regards customers, success as its own success. Let us develop prosperous future hand in hand for Aminoguanidine Dinitrate, 1-Aminoguanidiniumhydrogencarbonate, Aminoguanidine Hydrochloride Solubility Water, The continual availability of high grade products in combination with our excellent pre- and after-sales service ensures strong competitiveness in an increasingly globalized market.

Factory wholesale Guanidine Hydrochloride Drug - Aminoguanidine Hydrochloride – Hailun New Material Detail:

Product name:carbazamidine hydrochloride; (diaminomethylidene)hydrazinium chloride
Molecular Formula:CH6N4HCL
CAS：1937-19-5
Molecular Weight:110.55
Structural Formula:

Use:Pharmaceutical, veterinary drugs

Index name	Index Value
Appearance	White like crystalline powder
Content	≥98%	≥99%
Insoluble Substances	≤0.2%	≤0.1%
Loss on Drying	≤1.5%	≤1%
Ignition Residue	≤0.2%	≤0.1%
Iron Content(Fe)	10 ppm	6 ppm
Free Acid	≤0.8%	≤0.5%

preparation

Preparation of aminoguanidine hydrochloride: 9 g of aminoguanidine carbonate was put into a 250ml three port flask, 20ml of absolute ethanol was added, the solid was insoluble in anhydrous ethanol to form a suspension. Under stirring at room temperature, the mixture of 6ml 30% concentrated hydrochloric acid and 10ml of absolute ethanol was dropwise added until there was no bubble, and then stirring reaction was continued at room temperature for 1 hour. The obtained suspension was heated to dissolve the solid completely, and then it was naturally lowered to room temperature. After being moved to the refrigerator and placed overnight, the white rod-shaped crystal with melting point of 166-167 ℃ was obtained.

Application

Daidzein has a variety of pharmacological effects, prevention and treatment of a variety of diseases. Cn200910144204.1 reported that aminoguanidine hydrochloride can be used to prepare a chemically modified daidzein, namely, daidzein 7,4 ‘- oxy aminoguanidine acetate. The soybean aglycone 7,4 ‘- oxy aminoguanidine acetate is a prodrug compound, which releases the parent drug – daidzein under physiological conditions, and improves its water solubility by covalent binding.

The preparation of Daidzein 7,4 ′ - o-aminoguanidine acetate: 0.5g aminoguanidine hydrochloride was dissolved in 100ml acetone, 0.02g phase transfer catalyst, 0.5g anhydrous potassium carbonate, 0.5g 7,4 ′ - chloroacetyl daidzein and 0.02g I2 were added into the solution. The reaction was carried out at room temperature for 24 hours. Acetone was evaporated from the filtrate under reduced pressure, and then separated by silica gel column. The eluent was ethyl acetate ∶ petroleum ether When the ratio is 1 ∶ 2, the white powder solid is obtained.

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We rely upon strategic thinking, constant modernisation in all segments, technological advances and of course upon our employees that directly participate in our success for Factory wholesale Guanidine Hydrochloride Drug - Aminoguanidine Hydrochloride – Hailun New Material , The product will supply to all over the world, such as: South Korea, belarus, New Orleans, We insist on the principle of "Credit being primary, Customers being the king and Quality being the best", we are looking forward to the mutual cooperation with all friends at home and abroad and we will create a bright future of business.

This manufacturers not only respected our choice and requirements, but also gave us a lot of good suggestions, ultimately， we successfully completed the procurement tasks.