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Hot New Products Aminoguanidine Hydrochloride Usp - Aminoguanidine Hydrochloride – Hailun New Material

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We rely upon strategic thinking, constant modernisation in all segments, technological advances and of course upon our employees that directly participate in our success for Aminoguanidine Reactions, Aminoguanidine Bicarbonate Cas No, CAS# 1937-19-5, Besides, our company sticks to high quality and reasonable price, and we also offer good OEM services to many famous brands.
Hot New Products Aminoguanidine Hydrochloride Usp - Aminoguanidine Hydrochloride – Hailun New Material Detail:

Product name:carbazamidine hydrochloride; (diaminomethylidene)hydrazinium chloride
Molecular Formula:CH6N4HCL
CAS1937-19-5
Molecular Weight:110.55
Structural Formula:

yy1

 

Use:Pharmaceutical, veterinary drugs

Index name

Index Value

Appearance

White like crystalline powder

Content

98%

99%

Insoluble Substances

0.2%

0.1%

Loss on Drying

1.5%

1%

Ignition Residue

0.2%

0.1%

Iron Content(Fe)

10 ppm

6 ppm

Free Acid

0.8%

0.5%

preparation

Preparation of aminoguanidine hydrochloride: 9 g of aminoguanidine carbonate was put into a 250ml three port flask, 20ml of absolute ethanol was added, the solid was insoluble in anhydrous ethanol to form a suspension. Under stirring at room temperature, the mixture of 6ml 30% concentrated hydrochloric acid and 10ml of absolute ethanol was dropwise added until there was no bubble, and then stirring reaction was continued at room temperature for 1 hour. The obtained suspension was heated to dissolve the solid completely, and then it was naturally lowered to room temperature. After being moved to the refrigerator and placed overnight, the white rod-shaped crystal with melting point of 166-167 was obtained.

Application

Daidzein has a variety of pharmacological effects, prevention and treatment of a variety of diseases. Cn200910144204.1 reported that aminoguanidine hydrochloride can be used to prepare a chemically modified daidzein, namely, daidzein 7,4 ‘- oxy aminoguanidine acetate. The soybean aglycone 7,4 ‘- oxy aminoguanidine acetate is a prodrug compound, which releases the parent drug – daidzein under physiological conditions, and improves its water solubility by covalent binding.

The preparation of Daidzein 7,4 - o-aminoguanidine acetate: 0.5g aminoguanidine hydrochloride was dissolved in 100ml acetone, 0.02g phase transfer catalyst, 0.5g anhydrous potassium carbonate, 0.5g 7,4 - chloroacetyl daidzein and 0.02g I2 were added into the solution. The reaction was carried out at room temperature for 24 hours. Acetone was evaporated from the filtrate under reduced pressure, and then separated by silica gel column. The eluent was ethyl acetate petroleum ether When the ratio is 1 2, the white powder solid is obtained.

 

 


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Our commission is to serve our users and clients with best quality and competitive portable digital products for Hot New Products Aminoguanidine Hydrochloride Usp - Aminoguanidine Hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Sao Paulo, Curacao, UK, In the new century, we promote our enterprise spirit "United, diligent, high efficiency, innovation", and stick to our policy"basing on quality, be enterprising, striking for first class brand". We would take this golden opportunity to create bright future.
  • The factory workers have rich industry knowledge and operational experience, we learned a lot in working with them,we are extremely grateful that we can encount a good company has excellent wokers.
    5 Stars By Naomi from Vietnam - 2018.10.09 19:07
    Customer service staff and sales man are very patience and they all good at English, product's arrival is also very timely, a good supplier.
    5 Stars By Laura from Porto - 2018.11.11 19:52
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