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Hot-selling Polyhexamethyleneguanidine Hydrochloride - Aminoguanidine Hydrochloride – Hailun New Material

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Adhering into the principle of "quality, provider, performance and growth", we now have gained trusts and praises from domestic and intercontinental consumer for 3 Amino 1h 1 2 4 Triazole, 5 Nitro 2 Furaldehyde And Aminoguanidine Bicarbonate, 3-Amino-1 2 4-Triazol-5-One, As a key enterprise of this industry, our company makes efforts to become a leading supplier, based on the faith of professional quality & worldwide service.
Hot-selling Polyhexamethyleneguanidine Hydrochloride - Aminoguanidine Hydrochloride – Hailun New Material Detail:

Product name:carbazamidine hydrochloride; (diaminomethylidene)hydrazinium chloride
Molecular Formula:CH6N4HCL
CAS1937-19-5
Molecular Weight:110.55
Structural Formula:

yy1

 

Use:Pharmaceutical, veterinary drugs

Index name

Index Value

Appearance

White like crystalline powder

Content

98%

99%

Insoluble Substances

0.2%

0.1%

Loss on Drying

1.5%

1%

Ignition Residue

0.2%

0.1%

Iron Content(Fe)

10 ppm

6 ppm

Free Acid

0.8%

0.5%

preparation

Preparation of aminoguanidine hydrochloride: 9 g of aminoguanidine carbonate was put into a 250ml three port flask, 20ml of absolute ethanol was added, the solid was insoluble in anhydrous ethanol to form a suspension. Under stirring at room temperature, the mixture of 6ml 30% concentrated hydrochloric acid and 10ml of absolute ethanol was dropwise added until there was no bubble, and then stirring reaction was continued at room temperature for 1 hour. The obtained suspension was heated to dissolve the solid completely, and then it was naturally lowered to room temperature. After being moved to the refrigerator and placed overnight, the white rod-shaped crystal with melting point of 166-167 was obtained.

Application

Daidzein has a variety of pharmacological effects, prevention and treatment of a variety of diseases. Cn200910144204.1 reported that aminoguanidine hydrochloride can be used to prepare a chemically modified daidzein, namely, daidzein 7,4 ‘- oxy aminoguanidine acetate. The soybean aglycone 7,4 ‘- oxy aminoguanidine acetate is a prodrug compound, which releases the parent drug – daidzein under physiological conditions, and improves its water solubility by covalent binding.

The preparation of Daidzein 7,4 - o-aminoguanidine acetate: 0.5g aminoguanidine hydrochloride was dissolved in 100ml acetone, 0.02g phase transfer catalyst, 0.5g anhydrous potassium carbonate, 0.5g 7,4 - chloroacetyl daidzein and 0.02g I2 were added into the solution. The reaction was carried out at room temperature for 24 hours. Acetone was evaporated from the filtrate under reduced pressure, and then separated by silica gel column. The eluent was ethyl acetate petroleum ether When the ratio is 1 2, the white powder solid is obtained.

 

 


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Our products are greatly recognized and trustworthy by users and will fulfill continually shifting economic and social requires for Hot-selling Polyhexamethyleneguanidine Hydrochloride - Aminoguanidine Hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Angola, Vancouver, Irish, There are advanced producing & processing equipment and skilled workers to ensure the products with high quality. We have found an excellent before-sale, sale, after-sale service to ensure the customers that could rest assured to make orders. Until now our products are now moving on fast and very popular in South America, East Asia, the Middle east, Africa, etc.
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