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OEM/ODM Supplier Aminoguanidine Synthesis - Guanidine hydrochloride – Hailun New Material

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OEM/ODM Supplier Aminoguanidine Synthesis - Guanidine hydrochloride – Hailun New Material Detail:

Product name: Guanidine Hydrochloride

Aminoformamidine hydrochloride or Guanidinium chloride

Appearance: white or yellowish lump.

Physical property data

1. Character: white or yellowish lump

2. Melting point (℃): 181-183

3. Relative density (g / ml, 20 / 4 ℃): 1.354

4. Solubility: 228g in 100g water, 76g in 100g methanol and 24g in 100g ethanol at 20 ℃. Almost insoluble in acetone, benzene and ether.

5. PH value (4% aqueous solution, 25 ℃): 6.4

Properties and stability

This product is unstable and can be hydrolyzed into ammonia and urea in aqueous solution, so its toxicity is the same as that of urea. Guanidine and its derivatives are generally more toxic than urea.

Purpose:1. It can be used as intermediate of medicine, pesticide, dye and other organic synthesis. It can be used to synthesize 2-Aminopyrimidine, 2-amino-6-methylpyrimidine and 2-amino-4,6-dimethylpyrimidine. It is an intermediate for the manufacture of sulfadiazine, sulfamethylpyrimidine and sulfadimidine.

 

2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize anti anemia drug folic acid. It can also be used as antistatic agent for synthetic fibers.

 

3. It can also be used as protein denaturant.

 

  1. As a strong denaturant in the experiment of extracting total RNA. Guanidine hydrochloride solution can dissolve protein, cause cell structure damage, nuclear protein secondary structure damage, dissociate from nucleic acid, in addition, RNase can be inactivated by reducing agent such as guanidine hydrochloride.

synthetic method

Using dicyandiamide and ammonium salt (ammonium chloride) as raw materials, the crude guanidine hydrochloride was obtained by melting reaction at 170-230 ℃, and the finished product was obtained by refining.

Contact control

1. Do not inhale dust

2. Harmful if swallowed

3. Eye irritation

4. Skin irritation

Personal protection

1. Wear protective clothing to avoid direct contact or inhalation; 2. Do not drink, eat or smoke at work; 3. Use safety glasses


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We will make every effort to be outstanding and perfect, and accelerate our steps for standing in the rank of international top-grade and high-tech enterprises for OEM/ODM Supplier Aminoguanidine Synthesis - Guanidine hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Angola, Albania, panama, Wide selection and fast delivery to suit your needs! Our philosophy: Good quality, great service, keep improving. We've been looking forward that more and more oversea friends join in our family for further development near the future!
  • Adhering to the business principle of mutual benefits, we have a happy and successful transaction, we think we will be the best business partner.
    5 Stars By Bruno Cabrera from Bangladesh - 2017.08.18 11:04
    Cooperate with you every time is very successful, very happy. Hope that we can have more cooperation!
    5 Stars By Gloria from South Africa - 2018.09.21 11:44
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