PriceList for Aminoguanidine Hydrochloride Solubility Water - Aminoguanidine Hydrochloride – Hailun New Material
PriceList for Aminoguanidine Hydrochloride Solubility Water - Aminoguanidine Hydrochloride – Hailun New Material Detail:
Product name:carbazamidine hydrochloride; (diaminomethylidene)hydrazinium chloride
Molecular Formula:CH6N4HCL
CAS:1937-19-5
Molecular Weight:110.55
Structural Formula:
Use:Pharmaceutical, veterinary drugs
Index name |
Index Value |
|
Appearance |
White like crystalline powder |
|
Content |
≥98% |
≥99% |
Insoluble Substances |
≤0.2% |
≤0.1% |
Loss on Drying |
≤1.5% |
≤1% |
Ignition Residue |
≤0.2% |
≤0.1% |
Iron Content(Fe) |
10 ppm |
6 ppm |
Free Acid |
≤0.8% |
≤0.5% |
preparation
Preparation of aminoguanidine hydrochloride: 9 g of aminoguanidine carbonate was put into a 250ml three port flask, 20ml of absolute ethanol was added, the solid was insoluble in anhydrous ethanol to form a suspension. Under stirring at room temperature, the mixture of 6ml 30% concentrated hydrochloric acid and 10ml of absolute ethanol was dropwise added until there was no bubble, and then stirring reaction was continued at room temperature for 1 hour. The obtained suspension was heated to dissolve the solid completely, and then it was naturally lowered to room temperature. After being moved to the refrigerator and placed overnight, the white rod-shaped crystal with melting point of 166-167 ℃ was obtained.
Application
Daidzein has a variety of pharmacological effects, prevention and treatment of a variety of diseases. Cn200910144204.1 reported that aminoguanidine hydrochloride can be used to prepare a chemically modified daidzein, namely, daidzein 7,4 ‘- oxy aminoguanidine acetate. The soybean aglycone 7,4 ‘- oxy aminoguanidine acetate is a prodrug compound, which releases the parent drug – daidzein under physiological conditions, and improves its water solubility by covalent binding.
The preparation of Daidzein 7,4 ′ - o-aminoguanidine acetate: 0.5g aminoguanidine hydrochloride was dissolved in 100ml acetone, 0.02g phase transfer catalyst, 0.5g anhydrous potassium carbonate, 0.5g 7,4 ′ - chloroacetyl daidzein and 0.02g I2 were added into the solution. The reaction was carried out at room temperature for 24 hours. Acetone was evaporated from the filtrate under reduced pressure, and then separated by silica gel column. The eluent was ethyl acetate ∶ petroleum ether When the ratio is 1 ∶ 2, the white powder solid is obtained.
Product detail pictures:
Related Product Guide:
We persist with the principle of "quality 1st, assistance initially, continual improvement and innovation to meet the customers" for your management and "zero defect, zero complaints" as the standard objective. To great our service, we present the products and solutions while using the very good top quality at the reasonable cost for PriceList for Aminoguanidine Hydrochloride Solubility Water - Aminoguanidine Hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Holland, Egypt, The Swiss, With well educated, innovative and energetic staff, we are responsible for all elements of research, design, manufacture, sale and distribution. By studying and developing new techniques, we are not only following but also leading fashion industry. We listen attentively to the feedback from our customers and provide instant replies. You will instantly feel our professional and attentive service.
By Gemma from Armenia - 2017.12.09 14:01
The supplier cooperation attitude is very good, encountered various problems, always willing to cooperate with us, to us as the real God.
By Johnny from Belarus - 2018.03.03 13:09