Special Design for Inos Inhibitor Aminoguanidine - Guanidine hydrochloride – Hailun New Material
Special Design for Inos Inhibitor Aminoguanidine - Guanidine hydrochloride – Hailun New Material Detail:
Product name: Guanidine Hydrochloride
Aminoformamidine hydrochloride or Guanidinium chloride
Appearance: white or yellowish lump.
Physical property data
1. Character: white or yellowish lump
2. Melting point (℃): 181-183
3. Relative density (g / ml, 20 / 4 ℃): 1.354
4. Solubility: 228g in 100g water, 76g in 100g methanol and 24g in 100g ethanol at 20 ℃. Almost insoluble in acetone, benzene and ether.
5. PH value (4% aqueous solution, 25 ℃): 6.4
Properties and stability
This product is unstable and can be hydrolyzed into ammonia and urea in aqueous solution, so its toxicity is the same as that of urea. Guanidine and its derivatives are generally more toxic than urea.
Purpose:1. It can be used as intermediate of medicine, pesticide, dye and other organic synthesis. It can be used to synthesize 2-Aminopyrimidine, 2-amino-6-methylpyrimidine and 2-amino-4,6-dimethylpyrimidine. It is an intermediate for the manufacture of sulfadiazine, sulfamethylpyrimidine and sulfadimidine.
2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize anti anemia drug folic acid. It can also be used as antistatic agent for synthetic fibers.
3. It can also be used as protein denaturant.
- As a strong denaturant in the experiment of extracting total RNA. Guanidine hydrochloride solution can dissolve protein, cause cell structure damage, nuclear protein secondary structure damage, dissociate from nucleic acid, in addition, RNase can be inactivated by reducing agent such as guanidine hydrochloride.
synthetic method
Using dicyandiamide and ammonium salt (ammonium chloride) as raw materials, the crude guanidine hydrochloride was obtained by melting reaction at 170-230 ℃, and the finished product was obtained by refining.
Contact control
1. Do not inhale dust
2. Harmful if swallowed
3. Eye irritation
4. Skin irritation
Personal protection
1. Wear protective clothing to avoid direct contact or inhalation; 2. Do not drink, eat or smoke at work; 3. Use safety glasses
Product detail pictures:
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To create far more benefit for customers is our company philosophy; customer growing is our working chase for Special Design for Inos Inhibitor Aminoguanidine - Guanidine hydrochloride – Hailun New Material , The product will supply to all over the world, such as: Swaziland, Algeria, United Arab emirates, Our professional engineering group will always be ready to serve you for consultation and feedback. We are able to also offer you with absolutely free samples to meet your requirements. Finest efforts will likely be produced to give you the ideal service and goods. For anyone who is thinking about our company and merchandise, please contact us by sending us emails or contact us quickly. As a way to know our merchandise and firm. lot more, you can come to our factory to find out it. We'll always welcome guests from all over the world to our business to build company relations with us. Please feel free to get in touch with us for business and we believe we are going to share the top trading practical experience with all our merchants.
By Astrid from Plymouth - 2018.02.21 12:14
This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
By Daniel Coppin from Italy - 2018.11.02 11:11
